So I recently purchased the Land rover Defender Lego Technic set (42110) and have encountered one problem so far.
I am on Step 271 and it is where you assemble the bulk of the power train together. This uses bags 1 & 2.
This step is seemingly improbable as the gear you have to place sits too high up meaning you can't get the connecting rod through. At least on mine, it currently isn't locating properly.
Photos included
http://imgur.com/a/kUdVglv