I've heard multiple rumours of new Fire and Police line-up coming this winter. Also a space sub-theme is long overdue to update.
I believe we could also see 1 or 2 new City boats/ships.
Will point out Toothdominoes (A LEGO designer) on Twitter stated Clemence, from LEGO City Adventures head print was going to be real, so maybe more LEGO City Adventures tie in stuff?: