I don't physically own either yet (Cafe Corner has been dispatched but I haven't got my paws on it yet). I've obviously made my choice when I was trying to decide what to buy and picked CC over Town Plan. I did take a reasonable amount of time to consider.
Town Plan is an awesome set, it also has that special 50 year anniversary appeal. To me, the biggest advantage Town Plan has over CC though is playability for kids (which doesn't apply in the same way to AFOLs like us). Even although the buildings could be separate sets, there is something very appealing about getting them all in one big set as an instant bonanza. I especially like the 50s style architecture on the cinema.
However good as Town Plan is, the modular buildings such as CC just stomp all over it. They are breathtaking. They are on an entirely different level. The size and detail of these sets is astonishing. They are a townie AFOLs dream sets.
So my basic result would be: Town Plan (wins as a set for kids and adults who want to play with driving cars around Town Plans :-) ), CC (wins for adults).